Cellosaurus

The Cellosaurus is a knowledge resource on cell lines. It attempts to describe all cell lines used in biomedical research. Its scope includes: Immortalized cell lines, Naturally immortal cell lines (example: stem cell lines), Finite life cell lines when those are distributed and used widely, Vertebrate cell line with an emphasis on human, mouse and rat cell lines, Invertebrate (insects and ticks) cell lines. Its scope does not include: Primary cell lines (with the exception of the finite life cell lines described above), Plant cell lines. Cellosaurus was initiated to be used as a cell line controlled vocabulary in the context of the neXtProt knowledgebase, but it quickly become apparent that there was a need for a cell line knowledge resource that would serve the needs of individual researchers, cell line distributors and bioinformatic resources. This leads to an increase of the scope and depth of the content of the Cellosaurus. The Cellosaurus is a participant of the Resource Identification Initiative and contributes actively to the work of the International Cell Line Authentication Committee (ICLAC). It is a Global Core Biodata Resource, an ELIXIR Core Data Resource and an IRDiRC Recognized Resource.

Cellosaurus系一种关于细胞株的知识资源。其旨在描述生物医学研究中使用的所有细胞株。其涵盖范围包括：永生化细胞株、自然永生化细胞株（例如：干细胞株）、有限寿命细胞株在广泛分布和使用的情况下，以及以人类、小鼠和大鼠细胞株为主的脊椎动物细胞株，以及无脊椎动物（昆虫和蜱）细胞株。其不涵盖范围包括：原代细胞株（上述有限寿命细胞株除外）、植物细胞株。Cellosaurus最初被发起用作neXtProt知识库中细胞株控制词汇，但很快便显现出有必要建立一个能够满足个别研究人员、细胞株分销商和生物信息资源需求的细胞株知识资源。这促使Cellosaurus的内容范围和深度不断扩展。Cellosaurus是资源识别倡议的参与者，并积极贡献于国际细胞株鉴定委员会（ICLAC）的工作。它是全球核心生物数据资源、ELIXIR核心数据资源以及IRDiRC认可的资源。

搜集汇总

背景与挑战

背景概述

Cellosaurus是一个专注于生物医学研究中使用的细胞线的知识资源，涵盖了从人类到昆虫的广泛物种。它提供了超过165,949个细胞线的详细信息，支持开放获取，并通过FTP和REST API等多种方式访问数据。