Ro5-4864, a Ligand of the Mitochondrial Translocator Protein, Protects Against Heart Failure in Mice
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Protective effects of salidroside on chronic heart failure in rats and the underlying mechanisms
The present study aimed to investigate the protective effects of salidroside on chronic heart failure (CHF) in rats and to explore the underlying mechanisms. One hundred SD rats were randomly divided
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Neurons exert a pivotal role in the preservation of cardiac physiological function. However, there is a lack of explanation about the mechanism of cardiac neurons in the pathogenesis of cardiac dysfun
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Additional file 2: of Molecular features of biguanides required for targeting of mitochondrial respiratory complex I and activation of AMP-kinase
Individual data points for mouse heart mitochondria simultaneously uncoupled with ADP and inhibited with phenformin. (XLSX 56 kb)
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Mus musculus Raw sequence reads. Mus musculus
We show that the RNA binding protein Human antigen R is activated in the failing human heart and its inhibition, by genetic deletion or pharmacological inhibition, prevents the progression to heart fa
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A Porcine Model of Heart Failure With Preserved Ejection Fraction Induced by Chronic Pressure Overload Characterized by Cardiac Fibrosis and Remodeling. A Porcine Model of Heart Failure With Preserved Ejection Fraction Induced by Chronic Pressure Overload Characterized by Cardiac Fibrosis and Remodeling
In this study, we employed descending aortic constriction (DAC) technique to establish a minipig heart failure model. The cardiac phenotypes, pathological and cellular changes, fibrotic signaling acti
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