Table 1. Heart recovery parameters by E2 in WT, Esr1-/-, Esr2-/- and Gper1-/-

Cardiac functional parameters, left ventricular systolic pressure (LVSP); left ventricular end-diastolic pressure (LVEDP); left ventricular developed pressure (LVDP) and heart rate (HR) before ischemia (Basal) and at different times of reperfusion after ischemia with and without E2 treatment in WT, Esr1-/-, Esr2-/- and Gper1. Values are mean±SEM.; * P<0.05 WT-control versus WT+E2-treated group (n=4-6 hearts/ group). # P<0.05 Esr2-/--control versus Esr1-/-+E2-treated group (n=4-6 hearts/ group), + P<0.05 Esr2-/--control versus Esr2-/-+E2-treated group (n=4-6 hearts/ group).