YAP drives proliferation and tumorigenesis by recruiting Mediator to super- enhancer elements

NIAID Data Ecosystem2026-03-09 收录

癌症转录调控

增强子功能

数据链接：

https://www.ncbi.nlm.nih.gov/bioproject/PRJNA263634 数据链接链接失效反馈

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资源简介：

This SuperSeries is composed of the SubSeries listed below. Overall design: Refer to individual Series

创建时间：

2014-10-10

HSF1 drives a transcriptional program distinct from heat shock to support highly malignant human cancers

癌症转录调控

恶性肿瘤分子机制

This SuperSeries is composed of the following subset Series: GSE38232: HSF1 drives a transcriptional program distinct from heat shock to support highly malignant human cancers [gene expression] GSE389

NIAID Data Ecosystem90

Proteasome inhibition blocks estrogen-dependent gene transcription by decreasing histone H2B monoubiquitination in human breast cancer cells. Homo sapiens

癌症转录调控

蛋白酶体抑制

The estrogen receptor-alpha (ERα) determines breast cancer cell phenotype and is a prognostic indicator. A better understanding of the mechanisms controlling ERα function may uncover improved strategi

NIAID Data Ecosystem40

Transcriptional regulation in MCF-7 breast cancer cells treated with proteasome inhibitor MG132 [rna_polii_chIP-seq]

癌症转录调控

蛋白酶体抑制剂

We report whole genome chromatin immunoprecipitation followed by sequencing (ChIP-seq) of 3 different RNA Pol II CTD modifications in MCF-7 breast cancer cells treated with vehicle (UNTR) or the prote

NIAID Data Ecosystem20

RNA-seq of DEX induced and ethanol control Basal-like breast cancer cell lines

癌症转录调控

RNA测序基因表达分析

Breast cancers can be divided into subtypes with different prognoses and treatment responses based on global gene expression differences. This study utilized integrated analysis of DNA methylation,

NIAID Data Ecosystem80

Genes directly regulated by NF-κB in human hepatocellular carcinoma HepG2 [RNA-seq]

癌症转录调控

NF-κB靶基因

Over activation of NF-κB has close relationship with hepatitis and hepatocellular carcinoma (HCC). In this study, by manipulating NF-κB activity with its recognized activator TNFα and using ChIP-seq a

NIAID Data Ecosystem20

YAP drives proliferation and tumorigenesis by recruiting Mediator to super- enhancer elements

资源简介：

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