Characteristics of total cohort and subpopulation of children with genotype information for FLG variants.

*Genotyped subpopulation represents the number of children with genotype information for R501X, 2282del and S3247X FLG variants.†Two-sided one sample binomial tests were used to determine if statistical differences are present when comparing proportions for the genotyped subpopulation with their respective proportions in the total cohort.‡Skin prick tests were performed on symptomatic children (i.e. children with symptoms of eczema, asthma, or rhinitis) at age 1-or-2 years.