A multi-material photon-counting micro-CT dataset of mouse brain with voxel-wise cerebrovascular annotations

This record contains a multi-material photon-counting micro-CT dataset of the mouse brain with voxel-wise cerebrovascular annotations. The dataset includes ten male mice, comprising eight in vivo cases and two ex vivo cases acquired at higher spatial resolution. For each mouse, five spatially co-registered image volumes are provided: intracranial and skull-inclusive versions of the total-energy CT image and contrast-agent map, together with a skull-inclusive hydroxyapatite (HAP) map. One manually reviewed reference vessel mask is also provided for each case. All images and annotations within each case share the same voxel grid and are stored in compressed NIfTI format. The accompanying software archive contains the processing and analysis code used in this study, including PreSeg-2.5D training, validation and inference code, the XDoG vessel-candidate tool, VesselSpec inference code, model checkpoints, and usage documentation. File descriptions, archive organization and technical metadata are provided in README.md and metadata.xlsx. The dataset supports cerebrovascular segmentation, analysis of vessels near the cranial boundary, evaluation of segmentation methods, and multi-material image fusion studies.