Urine represents an ideal source of clinically relevant biomarkers since it contains a large number of proteins and low molecular weight peptides. Characterization of the normal urinary proteome and p
BackgroundAdrenal venous sampling (AVS) is recognized as the gold standard for subtyping primary aldosteronism (PA), but its invasive nature and technical challenges limit its availability. A recent s
Background and objectives Uromodulin, produced exclusively in the kidney’s thick ascending limb, is a biomarker of kidney tubular health. However, the relationship between urine uromodulin and hist
Summary Metabolites in human biofluids document individual physiological status. We conducted comprehensive, non-targeted, non-invasive metabolomic analysis of urine from 27 healthy human subjects, co
