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Analysis of gene expression changes during long-term induction of EMT in EpRas tumor cells by TGF-b1.. Mus musculus

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https://www.ncbi.nlm.nih.gov/bioproject/PRJNA257067
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EMT is a developmental process, which can be reactivated in cancer cells. Cancer cells maintaining EMT in the circulation may have pro-metastatic properties. We used microarrays to profile EMT-related gene expression changes after 14 d of TGF-b1 treatment. Overall design: EpRas cells were cultured in standard conditions either in the presence of absence of recombinant TGF-b1 (2 ng/ml) for 14 d. After this period, RNA was isolated from triplicate wells of treated and non-treated cells, and hybridized on Affymetrix microarrays.
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2014-07-30
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