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Identification of an alternative triglyceride biosynthesis pathway

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https://www.ncbi.nlm.nih.gov/bioproject/PRJNA979011
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Haploid genetic screens carried out in HAP1 cells using gene-trap mutagenesis (as described in Brockmann et al, Nature, 2017) for the abundance of lipid droplets that were detected by fluorescent labelling using Bodipy493/503. Screens were carried out in wild-type cells that were exposed to a 24hr pulse of oleic acid or in DGAT1/DGAT2 double knockout cells or in TMX1-deficient cells.
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2023-06-02
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