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Total Synthesis and Absolute Stereochemical Assignment of Kibdelone C

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NIAID Data Ecosystem2026-03-07 收录
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Kibdelones are hexacyclic tetrahydroxanthones and potent anticancer agents isolated from an Australian microbe. Herein, we describe the synthesis of a chiral, nonracemic iodocyclohexene carboxylate EF ring fragment of the kibdelones employing an intramolecular iodo halo-Michael aldol reaction and its merger with an ABCD ring fragment to afford the congener kibdelone C.

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2011-07-06
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