Evidence for a unique RNA motif in orchestrating Orthomyxoviridae splicing
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https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE202990
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资源简介：
Our laboratory has generated evidence that Archaean L7Ae serves as a unique inhibitor of orthomyxovirus splicing, and as such, can inhibit replication of this class of viruses. Here, we utilize RNA-sequencing to analyze how Archaean L7Ae impacts the transcriptome of a human cell line. Results showed that L7Ae had minimal impact on host transcriptonal response despite retaining its properties to inhibit orthomyxovirus replication. Comparative differential expression data between 293T cells that were transfected with pCAGGS-eGFP (control) or pCAGGs-L7ae (experimental) and harvested 24 hours post transfection
创建时间：
2023-03-13
