首页/数据集/Mus musculus strain:C57BL6 Raw sequence reads. Mus musculus strain:C57BL6

Mus musculus strain:C57BL6 Raw sequence reads. Mus musculus strain:C57BL6

NIAID Data Ecosystem2026-03-12 收录

免疫细胞发育表观遗传

T细胞功能调控

数据链接：

https://www.ncbi.nlm.nih.gov/bioproject/PRJNA765040 数据链接链接失效反馈

官方服务：

资源简介：

Epigenetic Programming during thymic development sets the stage for optimalfunction in effector T cells via DNA demethylation

应用场景：

创建时间：

2021-09-21

免疫代谢

T细胞功能调控

Sphingosine 1-phosphate (S1P), a pro-tumor survival bioactive lysophospholipid, generated by sphingosine kinase 1 (SphK1), regulates lymphocyte egress into circulation via transducing S1P receptor 1 (

NIAID Data Ecosystem50

Listeria monocytogenes induces T cell receptor unresponsiveness via its pore-forming toxin listeriolysin O

细菌免疫逃逸

T细胞功能调控

Listeria monocytogenes induces T cell receptor unresponsiveness via its pore-forming toxin listeriolysin O

ChEBI2010-07-29 更新00

ACSL4-programmed sphingomyelin metabolism rejuvenates tumor-infiltrating T-cells to enhance efficacy of anti-PD-1 immunotherapy (ATAC-seq)

免疫代谢

T细胞功能调控

Energy metabolism is central for the control of T-cell fate and functional status. Despite the clinical success of PD-1-targeted therapy, the metabolic mechanisms underlying the T cell unresponsivenes

NIAID Data Ecosystem00

Anti-PD-1 re-navigates concealed IL-15 to rejuvenate tumor-specific PD-1+CD8+T cells inside the tumor microenvironment

肿瘤免疫治疗

T细胞功能调控

The authors engineer an anti-PD-1-concealed sIL-15 fusion protein (aPD-1-IL-15-R), eliciting extraordinary antitumor immunity with negligible toxicity. aPD-1-IL-15-R largely expands tumor-specific CD8

NIAID Data Ecosystem20

Hypoxia-inducible factors enhance CD8+ T cell effector responses to persistent antigen.

肿瘤免疫微环境

T细胞功能调控

Hypoxia-inducible factors enhance CD8+ T cell effector responses to persistent antigen.

ChEBI2013-09-29 更新00