Crystal Structure of the first bromodomain of human BRD4 in complex with the inhibitor SLP-50
收藏Protein Data Bank Japan2023-11-29 更新2026-04-19 收录
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Crystal Structure of the first bromodomain of human BRD4 in complex with the inhibitor SLP-50 Descriptor: Bromodomain-containing protein 4, ~{N}-[2-ethyl-6-(4-methylpiperazin-1-yl)-3-oxidanylidene-2,7-diazatricyclo[6.3.1.0^{4,12}]dodeca-1(12),4,6,8,10-pentaen-9-yl]-2,4-bis(fluoranyl)benzenesulfonamide Authors: Zhang, C, Wang, C, Li, W, Zhang, Y, Xu, Y, Sun, L. Deposit date: 2022-01-12 Release date: 2022-08-10 Last modified: 2023-11-29 Method: X-RAY DIFFRACTION (1.82 Å) Cite: Design, synthesis, and anticancer evaluation of ammosamide B with pyrroloquinoline derivatives as novel BRD4 inhibitors. Bioorg.Chem., 127, 2022
创建时间：
2022-01-12
