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Identification of a Therapeutically Targetable JAK-STAT Enriched Androgen Receptor (AR) and AR Splice Variant Positive Triple Negative Breast Cancer Subtype

NIAID Data Ecosystem2026-05-01 收录

三阴性乳腺癌

JAK-STAT/AR靶向治疗

数据链接：

https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE244283 数据链接链接失效反馈

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资源简介：

This SuperSeries is composed of the SubSeries listed below. Refer to individual Series

应用场景：

创建时间：

2024-02-26

三阴性乳腺癌

STAT3转录调控

Breast cancer is a heterogeneous disease comprised of four molecular subtypes defined by whether the tumor-originating cells are luminal or basal epithelial cells. Breast cancers arising from the lumi

NIAID Data Ecosystem70

Supplementary Materials - Antitumor activity of new chemical compounds in triple negative mammary adenocarcinoma models

抗肿瘤药物

三阴性乳腺癌

Aims. According to the need for the development of new anticancer agents, we have synthetized novel bioactive compounds and aimed to determine their antitumor action. Materials & Methods. We d

DataCite Commons2024-05-18 更新40

Synergy of chemotherapy and macrophage depletion leads to T cell memory activation and durable triple negative breast cancer regression

癌症免疫治疗

三阴性乳腺癌

Chemotherapy and macrophage depletion leads to T cell memory activation and durable triple negative breast cancer regression in p53 null mouse models. Overall design: RNA-seq was performed on 15 'p53

NIAID Data Ecosystem20

SMARCA4 loss-of-function induces cisplatin resistance to activate YAP1-dependent epithelial-to-mesenchymal in triple negative breast cancer

三阴性乳腺癌

顺铂耐药性

We report transcriptome profiling (RNA-seq) for SMARA4 knock-out to elucidate the association with cisplatin-resistance and SMARCA4 loss-of-function using triple negative breast cancer cell lines. Ove

NIAID Data Ecosystem50

Keratin 19 binds and regulates cytoplasmic HNRNPK mRNA targets in triple-negative breast cancer. Keratin 19 binds and regulates cytoplasmic HNRNPK mRNA targets in triple-negative breast cancer

三阴性乳腺癌

细胞骨架-基因表达调控

This study identifies how a cytoskeletal protein can directly regulate gene expression by controlling the subcellular localization of RNA-binding proteins to support pathways involved in cancer progre

NIAID Data Ecosystem30

Identification of a Therapeutically Targetable JAK-STAT Enriched Androgen Receptor (AR) and AR Splice Variant Positive Triple Negative Breast Cancer Subtype

资源简介：

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