Additional file 1: of Bortezomib treatment induces a higher mortality rate in lupus model mice with a higher disease activity

is a table presenting significantly upregulated and downregulated genes in spleens of Bz-treated and Cyc-treated mice. Six hours after injection of 14-week-old MRL/lpr mice with vehicle (control, n = 4), Bz (n = 4), or Cyc (n = 3), mRNA of spleens was analyzed with SurePrint G3 Mouse GE 8 × 60 K Microarray (Agilent Technologies). Compared with control mice, significantly increased (>2-fold) and decreased (<0.5-fold) genes were extracted using Gene Spring software applying a modified t test. (XLSX 24 kb)