Structure of unphosphorylated human IRE1 bound to G-9807
收藏Protein Data Bank Japan2023-10-18 更新2026-03-21 收录
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Structure of unphosphorylated human IRE1 bound to G-9807 Descriptor: 4-[5-[2,6-bis(fluoranyl)phenyl]-2~{H}-pyrazolo[3,4-b]pyridin-3-yl]-2-(4-oxidanylpiperidin-1-yl)-1~{H}-pyrimidin-6-one, Serine/threonine-protein kinase/endoribonuclease IRE1 Authors: Lammens, A, Wang, W, Ferri, E, Rudolph, J. Deposit date: 2020-03-09 Release date: 2020-12-09 Last modified: 2023-10-18 Method: X-RAY DIFFRACTION (2.08 Å) Cite: Activation of the IRE1 RNase through remodeling of the kinase front pocket by ATP-competitive ligands. Nat Commun, 11, 2020
创建时间：
2020-03-09
