Abca1

ENCODES a protein that exhibits ATPase-coupled transmembrane transporter activity; high-density lipoprotein particle binding; apolipoprotein A-I binding (ortholog); INVOLVED IN cellular response to cholesterol; cellular response to cytokine stimulus; cellular response to xenobiotic stimulus; PARTICIPATES IN altered reverse cholesterol transport pathway; retinol metabolic pathway; reverse cholesterol transport pathway; ASSOCIATED WITH end stage renal disease; extrahepatic cholestasis; familial hyperlipidemia; FOUND IN basolateral plasma membrane; cell surface; apical plasma membrane (ortholog); INTERACTS WITH (25R)-cholest-5-ene-3beta,26-diol; (S)-nicotine; 17beta-estradiol

编码一种具有ATP酶偶联跨膜转运活性的蛋白质；高密度脂蛋白颗粒结合；载脂蛋白A-I结合（同源）；参与细胞对胆固醇的反应；细胞对细胞因子刺激的反应；细胞对外源物质刺激的反应；参与改变的逆向胆固醇转运途径；视黄醇代谢途径；逆向胆固醇转运途径；与终末期肾病、肝外胆汁淤积、家族性高脂血症相关；存在于基底外侧质膜；细胞表面；顶端质膜（同源）；与（25R）-胆笛-5-烯-3β,26-二醇；（S）-尼古丁；17β-雌二醇相互作用。