Delayed vs early cardioversion in patients with paroxysmal atrial fibrillation: a population-based study (2015–2020) - supplementary document

Aim: There is limited data on clinical outcomes of delayed cardioversion (DCV) compared with early cardioversion (ECV) in paroxysmal atrial fibrillation (AF) patients. Methods:We utilized data from National Inpatient Sample (2015–2020) and propensity-score matched analysis to determine adjusted odds ratio (aOR) of major clinical outcomes, including 17,879 AF cases: 9725 and 8154 underwent ECV and DCV, respectively. Results: Comparedwith ECV, DCV was associated with higher odds of acute heart failure (AHF) (aOR 1.79 [1.67–1.92]; p < 0.01), median length of stay (4 vs 2 days; p < 0.01), and cost of hospitalization ($33,410 vs $21,738; p < 0.01) with no significant difference in inpatient mortality and other cardiovascular and neurological outcomes. Conclusion: Compared with ECV, DCV was associated with more AHF and resource utilization.