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Polyploid cancer cells reveal signatures of chemotherapy relapse [scRNA-seq]

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NIAID Data Ecosystem2026-05-02 收录
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Treatment of PC3 and MDA-MB-231 cell lines with sublethal doses of docetaxel or cisplatin in vitro resulted in induction of polyploid cancer cells. Single cell copy RNA-sequencing was conducted to understand resistance of polyploid cancer cells to chemotherapy. Cells were treated with chemotherapy and allowed to recovery for 1 or 10 days in regular medium (days post treatment - DPT)

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2024-09-13
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