Exploring mechanism the transcription factor SIPA1 promote the progression of triple-negative breast cancer

To further study the regulation of SIPA1 on cells, the transcriptome sequencing on BT549 cells, BT549/shSIPA1 cells and si-dDBR cells were performed. We then performed gene expression profiling analysis using data obtained from RNA-seq of BT549 cells, BT549/shSIPA1 cells and si-dDBR cells to find the genes regulated by SIPA1. Overall design: Comparative gene expression profiling analysis of RNA-seq data for BT549 cells and its KD derivatives (shSIPA1, shSIPA1-dBD).