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Ruthenium(II) Porphyrin-Catalyzed Amidation of Aromatic Heterocycles

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https://figshare.com/articles/dataset/Ruthenium_II_Porphyrin_Catalyzed_Amidation_of_Aromatic_Heterocycles/3333079
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Ruthenium(II) porphyrin-catalyzed amidation of aromatic heterocycles with iminoiodanes under mild conditions (CH2Cl2, 4 Å molecular sieves, ultrasound, 40 °C) was achieved in moderate to good yields (up to 84%) and conversions (up to 99%). Only the N,N-ditosylamidated product was obtained for reactions involving heteroarenes, where X = O, S, or NTs. N-Alkyl- and N-aryl-substituted pyrroles, on the other hand, were shown to give the 3,4-diaminated adduct.
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2016-05-06
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