Enhancing Proteasome-Dependent Targeted Protein Degradation by mTOR inhibition

Name: Enhancing Proteasome-Dependent Targeted Protein Degradation by mTOR inhibition
Creator: ShanghaiTech University
Published: 2025-06-23T17:33:06+08:00

integrated proteome resources2026-07-03 收录

靶向蛋白质降解

mTOR信号通路调控

数据链接：

https://www.iprox.cn/page/project.html?id=IPX0012349000 数据链接链接失效反馈

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资源简介：

Enhancing Proteasome-Dependent Targeted Protein Degradation by mTOR inhibition

提供机构：

ShanghaiTech University

创建时间：

2025-06-23

Additional file 10 of Cullin-RING ligase BioE3 reveals molecular-glue-induced neosubstrates and rewiring of the endogenous Cereblon ubiquitome

靶向蛋白质降解

分子胶药物机制

Supplementary Material 10. Supplementary Table 2. LC-MS/MS processed data of CRBN BioE3 with proteasomal inhibitor bortezomib, with or without NEDDylation inhibitor MLN4924. Gene Ontology analysis of

NIAID Data Ecosystem50

DataSheet1_Cinobufagin alleviates lipopolysaccharide-induced acute lung injury by regulating autophagy through activation of the p53/mTOR pathway.ZIP

急性肺损伤

mTOR信号通路调控

Acute lung injury (ALI) is a severe clinical disorder characterized by dysregulated inflammatory responses, leading to high rates of morbidity and mortality. Cinobufagin, a primary component isolated

NIAID Data Ecosystem10

LncRNA HCP5 promotes malignant cell behaviors in esophageal squamous cell carcinoma via the PI3K/AKT/mTOR signaling

食管鳞状细胞癌分子病理机制

mTOR信号通路调控

The role of lncRNA HCP5 in esophageal squamous cell carcinoma (ESCC) remains unknown despite its involvement in different malignancies. MTT assay, EdU assay, TUNEL assay, transwell assay, and sphere f

Taylor & Francis Group2024-02-13 更新10

DataSheet_10_Celastrol Suppresses Glioma Vasculogenic Mimicry Formation and Angiogenesis by Blocking the PI3K/Akt/mTOR Signaling Pathway.zip

胶质母细胞瘤治疗

mTOR信号通路调控

Angiogenesis and vasculogenic mimicry (VM) are thought to be the predominant processes ensuring tumor blood supply during the growth and metastasis of glioblastoma (GBM). Celastrol has potential anti-

NIAID Data Ecosystem40

Expression data from HEK293T cells infected with Shigella or treated with Rapamycin. Homo sapiens

志贺氏菌感染转录组

mTOR信号通路调控

Shigella is an intracellular bacterial pathogen known to activate numerous innate immunity and inflammatory signaling pathways. Many of these pathways are also involved in mTOR signaling. We used HEK2

NIAID Data Ecosystem10

Enhancing Proteasome-Dependent Targeted Protein Degradation by mTOR inhibition

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