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Aberrant gene expression leakage from linage-specific heterochromatic loci during senescence

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NIAID Data Ecosystem2026-03-12 收录
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https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE130457
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To understand induction of cornification genes on lineage appropriate (keratinocyte differentiation) and inappropriate (fibroblast senescence) conditions , we generated histone modification and gene expression dataset. Then we compared these keratinocyte's dataset with our previous fibroblast senescence dataset in the study. Histone modification and mRNA profiles of proliferating and differentiated keratinocytes were generated.
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2021-01-04
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