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Transcription profiling of pancreatic buds from wild type and Ipf1/Pdx1 knock-out mouse embryos

ChEBI2008-02-12 更新2026-07-21 收录

胰腺发育调控

基因敲除模型转录组

数据链接：

https://www.ebi.ac.uk/biostudies/ArrayExpress/studies/E-MEXP-1047 数据链接链接失效反馈

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资源简介：

Transcription profiling of pancreatic buds from wild type and Ipf1/Pdx1 knock-out mouse embryos

应用场景：

创建时间：

2008-02-12

干细胞衰老

基因敲除模型转录组

We collected significant amount of phenotypic and mechanistic data from a ATF4 knockout mouse model and demonstrated that HSC defects with an aging-like phenotype (expanded pool of phenotypical HSCs,

NIAID Data Ecosystem80

Mesenchymal Igf2 is a major regulator of pancreatic growth and function. Mus musculus

胰腺发育调控

间充质Igf2信号

The genetic mechanisms that determine the size of the adult pancreas are not fully understood. Here we address the importance of the imprinted Igf2 gene for growth and function of the mouse pancreas.

NIAID Data Ecosystem60

Adipocyte- Specific FFA2 Deletion Leads to Increased Adipose Inflammation and Is Associated with Altered Intestinal Lipid Handling

脂肪组织

基因敲除模型转录组

Obesity and related metabolic disorders are often characterized by chronic adipose tissue inflammation, driving systemic insulin resistance and general metabolic dysfunction. Free Fatty Acid Receptor

NIAID Data Ecosystem30

Table S3. All significantly dysregulated genes in scWAT

脂肪组织差异表达基因

基因敲除模型转录组

List of all significant differentially expressed genes in scWAT from Adipo-HuR-/- mice.

NIAID Data Ecosystem80

Pancreas agenesis mutations disrupt a lead enhancer controlling a developmental enhancer cluster

胰腺发育调控

基因增强子功能

Genome-wide maps of H3K27ac, Mediator and PTF1A binding in stage-4 human multipotent pancreatic progenitor cells ChIP-Seq datasets (n=2) of H3K27ac, Mediator and PTF1A binding from in vitro derived h

NIAID Data Ecosystem40

Transcription profiling of pancreatic buds from wild type and Ipf1/Pdx1 knock-out mouse embryos

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