P28.ET0213, ET0318, ET0267 Datasets

Cytosine methylation data generated on mammalian methylation platform All bulk tissue samples and sorted cell populations were harvested from mice. Sorted cells populations were isolated using fluorescence-activated cell sorting. Bulk tissues analyzed in this work include muscle and peripheral blood. Sorted cell populations include muscle stem cells (satellite cells), fibroadipogenic progenitors, endothelial cells, hematopoietic cells (both from muscle and bone marrow), intestinal stem cells, differentiated intestinal epithelial cells, hematopoietic stem & progenitor cells, lymphoid progenitors, myeloid progenitors, B-cells, T-cells, and granulocytes. Pax7-nGFP and Lgr5-eGFP transgenic reporter mouse strains were used to sort satellite cells and intestinal stem cells respectively; all other experiments were conducted with C57BL6 mice. Mice of various pre-specified ages were used.