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Raw data - Synthesis and Pharmacological Evaluation of a Novel Peptide Based on Anemonia sulcata BDS-I Toxin as a New KV 3.4 Inhibitor Exerting a Neuroprotective Effect Against Amyloid-beta Peptide

NIAID Data Ecosystem2026-03-11 收录

神经保护药物研发

离子通道抑制剂

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Research data

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创建时间：

2020-05-15

GluN2B选择性拮抗剂

神经保护药物研发

A chiral pool synthesis was developed to obtain all four stereoisomeric 2-methyl-3-(4-phenylbutyl)tetrahydro-3-benzazepin-1-ols 21, 31, and 32 in a seven- to eight-step sequence. The phenols 32 revea

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Neuroprotective compounds identified through high-throughput screening of the Prestwick Chemical Library.

神经保护药物研发

缺血性脑损伤模型

1Compounds previously investigated in models of cerebral ischemia are italicized.

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My Data

视网膜色素变性治疗

神经保护药物研发

Selective inhibitors of the TrkC.T1 receptor reduce retinal inflammation, and delay neuronal death in a mice model of Retinitis Pigmentosa

Figshare2025-01-29 更新10

Table S1 - Fractionation of a Herbal Antidiarrheal Medicine Reveals Eugenol as an Inhibitor of Ca 2+ -Activated Cl − Channel TMEM16A

离子通道抑制剂

结构活性关系

Structure-activity analysis of eugenol analogs. TMEM16A inhibition was measured by fluorescence plate reader assay. (DOC)

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Table4_Construction Immune Related Feed-Forward Loop Network Reveals Angiotensin II Receptor Blocker as Potential Neuroprotective Drug for Ischemic Stroke.DOCX

神经保护药物研发

缺血性脑卒中免疫调控网络

Ischemic stroke (IS) accounts for the leading cause of disability and mortality in China. Increasing researchers are studying the effects of neuroprotective agents on IS. However, the molecular mechan

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Raw data - Synthesis and Pharmacological Evaluation of a Novel Peptide Based on Anemonia sulcata BDS-I Toxin as a New KV 3.4 Inhibitor Exerting a Neuroprotective Effect Against Amyloid-beta Peptide

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