Transcriptome sequence of Human bladder cancer cell line

Circular RNAs (circRNAs) have been increasingly indicated to be important participants in the development and progression of various malignant tumors. In this study, we re-analyzed circRNA high-throughout sequencing from human bladder cancer tissues and paired adjacent normal tissues. Then, we discover that a circRNA hsa_circ_0000591, named as circMGA, is significantly downregulated in bladder cancer. FISH assay has been proved that hsa_circ_0008399 mainly located in cytoplasm. Transcriptome analysis was performed to find the potential genes that could be regulated by circMGA. Overall design: Examination overexpression of circMGA in human bladder cancer