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Bordetella pertussis autoagglutination

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NIAID Data Ecosystem2026-03-14 收录
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https://www.ncbi.nlm.nih.gov/sra/DRP009483
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We have found that some B. pertussis isolates exhibit autoagglutination (Agg) phenotype when cultured on a synthetic cyclodextrin solid medium. The Agg did not occur in the presence of MgSO4, Nicotinic acid or when the bacterium was cultured on Bordet-Gengou agar. To determine the causal factor in autoagglutination of B. pertussis, we first isolated the non-agglutination mutant (designated as BP300s) from the strong Agg clinical isolate (BP300) by repeating single colony isolation from supernatant. By whole genome sequencing, two point mutations were found.
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2023-01-20
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