During pancreas development, endocrine progenitors differentiate into the islet-cell subtypes, which undergo further functional maturation in postnatal islet development. In islet b-cells, genes invol

NIAID Data Ecosystem50

Histone ChIP-seq from BLaER1 (ENCSR634UTP)

表观遗传学

组蛋白修饰

H4K20me1 ChIP-Seq on BLaER1 cell line after 12 h treatment with 100 nM 17β-estradiol, 10 ng/mL Interleukin-3, 10 ng/mL CSF1. For data usage terms and conditions, please refer to http://www.genome.gov

NIAID Data Ecosystem10

H4K20me3 controls Ash1-mediated H3K36me3 and transcriptional silencing in facultative heterochromatin

组蛋白修饰

兼性异染色质转录沉默

Normalized ChIP-seq datasets for visualization in IGV. The tracks contain means of pooled replicate datasets. ChIP-seq data were quality-filtered and adapters removed with trimmomatic v.0.39 (Bolger e

Zenodo2023-01-26 更新50

Embryonic Stem Cell Specific “Master” Replication Origins at the Heart of the Loss of Pluripotency

胚胎干细胞表观遗传学

复制起始机制

Epigenetic regulation of the replication program during mammalian cell differentiation remains poorly understood. We performed an integrative analysis of eleven genome-wide epigenetic profiles at 100

Figshare2016-01-15 更新40

The H3K36me2 methyltransferase Nsd1 Demarcates PRC2-mediated H3K27me2 and H3K27me3 Domains in Embryonic Stem Cells.

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