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Crystal structure of the GluA2 ligand-binding domain (S1S2J) in complex with the positive allosteric modulator TDPAM01 at 1.4 A resolution.

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Protein Data Bank Japan2024-11-06 更新2026-03-21 收录
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Crystal structure of the GluA2 ligand-binding domain (S1S2J) in complex with the positive allosteric modulator TDPAM01 at 1.4 A resolution. Descriptor: 1,2-ETHANEDIOL, 6,6'-(Ethane-1,2-diyl)bis(4-methyl-3,4-dihydro-2H-1,2,4-benzothiadiazine 1,1-dioxide), ACETATE ION, ... Authors: Nielsen, L, Laulumaa, S, Kastrup, J.S. Deposit date: 2017-12-18 Release date: 2018-11-21 Last modified: 2024-11-06 Method: X-RAY DIFFRACTION (1.4 Å) Cite: Enhancing Action of Positive Allosteric Modulators through the Design of Dimeric Compounds. J. Med. Chem., 61, 2018
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2017-12-18
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