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Crystal structure of DDB1-CRBN-BRD4(BD1) complex bound to dBET55 PROTAC.

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Protein Data Bank Japan2023-10-04 更新2026-03-21 收录
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Crystal structure of DDB1-CRBN-BRD4(BD1) complex bound to dBET55 PROTAC. Descriptor: Bromodomain-containing protein 4, DNA damage-binding protein 1,DNA damage-binding protein 1, Protein cereblon, ... Authors: Nowak, R.P, DeAngelo, S.L, Buckley, D, Bradner, J.E, Fischer, E.S. Deposit date: 2017-11-16 Release date: 2018-06-06 Last modified: 2023-10-04 Method: X-RAY DIFFRACTION (3.990035 Å) Cite: Plasticity in binding confers selectivity in ligand-induced protein degradation. Nat. Chem. Biol., 14, 2018

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2017-11-16
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