Expression of genes in THP-1 macrophages in response to C. glabrata wt, Cgvps34Δ and Cgyps(1-11)Δ cells.

To understand the host response of C. glabrata, we have employed the whole genome microarray expression profiling to identify the differentially regulated genes. For this, differentiated THP-1 cells were infected with C. glabrata wt, Cgvps34Δ and Cgyps(1-11)Δ cells for 6 h. Uninfected THP-1 cells, treated with PBS were taken as control. Total RNA was extracted using TriZol Reagent followed by ethonol precipitation. The experiments were performed in biological duplicate. Organism : Homo sapiens, Agilent's Human Gene Expression 8x60k Array (AMADID: 039494), Experiments were done in biological duplicates.