aMice were treated i.p. with 100 µg of MAb at the indicated days before or after challenge with 1000 LD50 of the mouse-adapted Ebola virus.bData for animals that died (number of animals in calculation
aMice were treated i.p. with various doses of the MAb 1 dpi with 1000 LD50 of the MA-ZEBOV. The survival of the mice was followed.bData for animals that died (number of animals in parentheses).cN/A: n
Male 200 gram HSD were co-injected i.v. with LeTx (40 µg PA+12 µg LF) alone or in combination with RDI-eIgG1. Number of surviving animals in each study and the average time to death (in hours) is repo