Functional residues in proteins tend to be highly conserved over evolutionary time. However, to what extent functional sites impose evolutionary constraints on nearby or even more distant residues is

Figshare2016-05-04 更新50

Magnitude and pattern of dynamic lesion effects.

脑网络分析

突变与病变效应分析

Lesions are tabulated as in Table 1. Magnitude of lesion effects measures: z′ = sum of all significantly

NIAID Data Ecosystem30

Alignment of functional residues

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