EPI-2021-0133 Suppl. Data
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Supplementary Table
1. Primers used for COBRA, RT- and Copy Number- qPCRs.
Supplementary
table 2: List of Log2 fold-change values of genes in Tet/Tet neurons and
their corresponding values described by CommonMind Consortium (CMC),
PsychENCODE and Brain Seq.
Supplementary
Table 3: Gene ontology and pathway enrichment analysis of 1135 dysregulated
genes in Tet/Tet neurons
Supplementary
Table 4: Disease ontology of 1135 dysregulated genes in Tet/Tet neurons.
Supplementary
Table 5: List of Log2 fold-change values of genes in Tet/Tet ESCs and their
corresponding values described by CommonMind Consortium (CMC), PsychENCODE
and Brain Seq.
Supplementary
Table 6: Gene ontology and pathway enrichment analysis of 170 dysregulated
genes in Tet/Tet ESCs.
Supplementary Table 7: Disease ontology of 170
dysregulated genes in
Tet/Tet ESCs.
Supplementary
Table 8: List of Log2 fold-change values of genes in Tet/Tet ESCs, Tet/Tet
neurons and their corresponding values described by CommonMind Consortium
(CMC), PsychENCODE and Brain Seq.
Supplementary
Table 9. List of imprinted genes showing dysregulation and hypomethylation in
Tet/Tet neurons. Imprinted genes associated with Schizophrenia are shown in
red.
Supplementary
Table 10. Analysis of methylation of repeat elements in Tet/Tet ESCs. Total
reads (hypermethylated + hypomethylated) less than 20 were not considered.
Supplementary Figure 1: COBRA assay of Snrpn,
H19, Igf2r, IAP and LINE-1 elements. -: no enzyme control; +: reactions
incubated with with Taqα1 (H19 and LINE-1) or HpyCH4IV (Snrpn, Igf2r and IAP).
Presence of digested fragments indicates methylation. M- Marker
提供机构：
Taylor & Francis
创建时间：
2021-10-14
