Additional file 2 of Mapping in silico genetic networks of the KMT2D tumour suppressor gene to uncover novel functional associations and cancer cell vulnerabilities

Additional file 2: Table S2. WRN KO and WRN inhibitor treatment validated cell lines. A. List of DepMap cell lines previously for WRN survival dependence using WRN KO assays. DepMap_ID: DepMap cell line id. Cell_line_name: Name of cell line. Author: name of publication WRN KO assay was performed in. WRN_dependence: outcome of WRN KO (TRUE indicates that WRN was essential for survival and FALSE indicates that it was not). B. Mutations found in MMR genes and KMT2D in cell lines in A. C-D. Shows a list of DepMap cell lines (C) and their MMR gene and KMT2D (D) mutations treated with WRN inhibitors.