Ten most discriminative numerical variables per time phase sorted by effect size defined as e = 2|AUROC-0.5| and calculated via univariate Mann-Whitney U tests on the training set.

The effect direction is indicated by (+)/ (–). P-values are FDR corrected with alpha = 0.05. Significant variables are included solely (all P-values < .001). Missing rates are reported as fraction of patients having values for a given variable from all patients. For time-resolved measurements, performance of aggregate scores is reported, where the 10th, 50th, and 90th percentiles are denoted as p10, p50, and p90, the median absolute deviation is denoted as map, and the sum across time is denoted as sum. Time invariant (TI), preoperative (T1), intraoperative (T2) and postoperative (T3) variables are included.