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Structure of hPNMT with inhibitor 3-fluoromethyl-7-thiomorpholinosulfonamide-THIQ and AdoMet

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Protein Data Bank Japan2024-10-30 更新2026-03-21 收录
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https://pdbj.org/mine/summary/2g72
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Structure of hPNMT with inhibitor 3-fluoromethyl-7-thiomorpholinosulfonamide-THIQ and AdoMet Descriptor: (3R)-3-(FLUOROMETHYL)-7-(THIOMORPHOLIN-4-YLSULFONYL)-1,2,3,4-TETRAHYDROISOQUINOLINE, Phenylethanolamine N-methyltransferase, S-ADENOSYLMETHIONINE Authors: Tyndall, J.D.A, Gee, C.L, Martin, J.L. Deposit date: 2006-02-27 Release date: 2007-02-13 Last modified: 2024-10-30 Method: X-RAY DIFFRACTION (2 Å) Cite: Enzyme Adaptation to Inhibitor Binding: A Cryptic Binding Site in Phenylethanolamine N-Methyltransferase J.Med.Chem., 50, 2007
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2006-02-27
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