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Additional file 7 of Association of hyperactivated transposon expression with exacerbated immune activation in systemic lupus erythematosus

NIAID Data Ecosystem2026-05-02 收录

自身免疫性疾病

转座子分析

数据链接：

https://figshare.com/articles/dataset/Additional_file_7_of_Association_of_hyperactivated_transposon_expression_with_exacerbated_immune_activation_in_systemic_lupus_erythematosus/27263378 数据链接链接失效反馈

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资源简介：

Supplementary Material 7.

应用场景：

创建时间：

2024-10-19

自身免疫性疾病

医学研究

原发性硬化性胆管炎是一种导致肝脏小胆管破坏的自身免疫性疾病。进展缓慢但不可抗拒，最终导致肝硬化和肝功能失代偿。该病至少从 1851 年开始就得到认可，并于 1949 年被命名为“原发性胆汁性肝硬化”。由于肝硬化只是晚期疾病的特征，因此患者权益团体在 2014 年提议将其名称更改为“原发性胆汁性胆管炎”。该数据来自于 1974 年至 1984 年间在 PBC 进行的 Mayo Clinic 试验。

OpenDataLab2026-07-12 更新1610

Additional file 1 of Systematic single-cell analysis reveals dynamic control of transposable element activity orchestrating the endothelial-to-hematopoietic transition

转座子分析

基因组学

Additional file 1: Table S1. TE families, superfamilies and classes in human. Table S2. TE families, superfamilies and classes in mouse. Table S3. Genome coverage of TEs in human. Table S4. Genome cov

DataCite Commons2024-09-11 更新60

Transposable elements analysed in this study.

转座子分析

染色质修饰

Classification of TEs, estimated copy numbers and approximate location of the amplicons used to survey chromatin modification states via chromatin immunoprecipitation (ChIP). Nine out of the ten eleme

NIAID Data Ecosystem50

CRAC channel controls the differentiation of pathogenic B cells in lupus nephritis

自身免疫性疾病

细胞分化调控

Systemic lupus erythematous (SLE) is a prototype of autoimmune disease. Lupus nephritis (LN) is one of the most serious complications of SLE. The development of autoreactive B cells and the production

NIAID Data Ecosystem60

Transcriptional profiling of human in vitro primed Th1, Th2, Th9 and Treg T cells. Transcriptional profiling of human in vitro primed Th1, Th2, Th9 and Treg T cells

T细胞亚群转录组学

自身免疫性疾病

To test whether human in vitro primed Th9 cells recapitulate the core pathogenic Th2 cell phenotype, we differentiated naïve T cells into Th1 (IL-12), Th2 (IL-4), Th9 (IL-4+TGF-β), and iTreg (TGF-β).

NIAID Data Ecosystem60

Additional file 7 of Association of hyperactivated transposon expression with exacerbated immune activation in systemic lupus erythematosus

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