Specific targeting of plasmids with Argonaute enables genome editing
收藏NIAID Data Ecosystem2026-05-01 收录
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https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE200694
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资源简介：
Prokaryotic Argonaute nuclease induces DNA interference between plasmid and chromosomal DNA to promote genome recombineering Argonaute-associated smDNA from E.coli transformed by plasmids of different constructions was analysed to elucidate the requirements for genomic DNA cleavage by CbAgo during DNA interference and integration of plasmid-encoded sequences into the homologous chromosomal locus Second part of data on DNA interference research. Additional libraries from 2 clones were prepared to show the integration of plasmid-encoded genes into the homologous chromosomal locus promoted by bacterial Argonaut protein
创建时间：
2023-03-30
