Boosting ATM activity alleviates ageing and extends lifespan in a mouse model of progeria.
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https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE109280
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资源简介：
Protein deacetylase SIRT6 and protein kinase ATM both decline during aging, which are of importance in regualtion of glucose metabolism . To explore the mechnisms of SIRT6 and ATM in glycolysis, we analysed the gene expressions in murine embryonic fibroblast cells generated from wildtype, Sirt6-/-, or Atm-/- mice. The mRNA profiles of MEF cells from wildtype, Sirt6-/-, or Atm-/- not were generated by deep sequencing using Illumina HiSeq x ten
创建时间：
2019-03-01
