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Networking of differentially expressed genes in human MIA PaCa2 pancreatic cancer cells resistant to methotrexate
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创建时间：
2025-01-24
相关数据集
SRSF3-mediated regulation of N6-methyladenosine modification-related lncRNA ANRIL splicing in promotion of pancreatic cancer resistance to gemcitabine I. SRSF3-mediated regulation of N6-methyladenosine modification-related lncRNA ANRIL splicing in promotion of pancreatic cancer resistance to gemcitabine I
Serine/arginine-rich splicing factor 3 (SRSF3) functions to regulate mRNA alternative splicing, a molecular mechanism to process more than 90% of the protein-coding genes and provides an essential sou
NIAID Data Ecosystem50
Transcriptomic analysis of Panc10.05 cells treated with indisulam
Indisulam is an abandoned drug that acts as a molecular glue, inducing degradation of splicing factor RBM39 through interaction with CRL4DCAF15. We generated spontaneoulsy indisulam-resistant Panc10.0
NIAID Data Ecosystem30
Table_2_Application of weighted co-expression network analysis and machine learning to identify the pathological mechanism of Alzheimer's disease.CSV
Aberrant deposits of neurofibrillary tangles (NFT), the main characteristic of Alzheimer's disease (AD), are highly related to cognitive impairment. However, the pathological mechanism of NFT formatio
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Effects of a quadruplex-binding compound on gemcitabine resistant pancreatic cancer cells
Changes in gene expression in a pancreatic cancer cell line and a chemoresistant line on treating with the drug CM03 Overall design: Changes at 6 h and 24 h were evaluated with RNA-seq with respect to
NIAID Data Ecosystem40
HDAC5 Deficiency Induces Intrinsic Resistance to KRASG12D Inhibition by Disrupting c-Myc Acetylation-Ubiquitination Homeostasis [RNA-seq]
We found that HDAC5 deletion significantly enhances intrinsic resistance to MRTX1133 in KRASG12D mutant pancreatic cancer. Mechanistic studies show that HDAC5 deletion promotes resistance to KRASG12D
NIAID Data Ecosystem20
