Drug-induced blockade of the human ether-à-go-go-related gene (hERG) channel is today considered the main cause of cardiotoxicity in postmarketing surveillance. Hence, several ligand-based approaches
Pressure–volume (PV) analysis was performed under isoflurane anesthesia with an oxygen mixture. Mice were intubated and ventilated using a pressure-controlled rodent ventilator. An admittance catheter
