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Processed source data and analysis code for evidence-bounded SGTA transcriptomic and proteomic analysis in lung adenocarcinoma

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Zenodo2026-07-28 更新2026-08-01 收录
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This research compendium contains analysis scripts, processed statistical outputs, figure-level source data, figure previews, provenance records, and audit files supporting a multi-omic study of SGTA in lung adenocarcinoma. Version 1.2.1 retains the complete-pair RNA–protein, patient-subsampling, same-tree cluster, and exact-size matched-module analyses introduced in v1.2.0; restores the public PDC000489 retrieval script; and adds reviewer-requested proteome-wide effect context, leave-one-protein-out module-membership sensitivity, collinearity and reduced-model diagnostics, and exploratory tumour-purity and protein-composition sensitivities. The analyses establish reproducible SGTA protein elevation but limit network inference to descriptive edge concordance conditional on frozen discovery membership; they do not establish stable membership or SGTA-specific network organisation. No new primary patient or experimental data were generated. Raw TCGA, GEO, CPTAC/PDC, and DepMap matrices are not redistributed. Original code in code/ is licensed under MIT; study-generated processed outputs, figure source data, figure previews, provenance, and documentation are licensed under CC BY 4.0.Administrative correction (28 July 2026): Outdated authorship metadata in legacy manuscript-building materials were corrected. This administrative correction does not affect the data, analyses, figures, results, or scientific conclusions.

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Zenodo
创建时间:
2026-07-19
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