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Dual Roles of Sulfonyl Hydrazides: A Three-Component Reaction To Construct Fully Substituted Pyrazoles Using TBAI/TBHP

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Figshare2016-02-17 更新2026-04-29 收录
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https://figshare.com/articles/dataset/Dual_Roles_of_Sulfonyl_Hydrazides_A_Three_Component_Reaction_To_Construct_Fully_Substituted_Pyrazoles_Using_TBAI_TBHP/2281137
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A mild and rapid approach has been developed for the construction of fully substituted pyrazoles using TBAI as a catalyst and TBHP as an oxidant, in which tosylhydrazide functions as the ring component and sulfonyl precursor. This protocol features a wide substrate scope with a broad range of functional group tolerance, utilizes easily available starting materials, can be scaled-up, and is operationally simple.
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2016-02-17
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