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Crystal Structures of Protein Kinase B Selective Inhibitors in Complex with Protein Kinase A and Mutants

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Protein Data Bank Japan2024-11-20 更新2026-03-21 收录
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Crystal Structures of Protein Kinase B Selective Inhibitors in Complex with Protein Kinase A and Mutants Descriptor: N-[4-({4-[5-(DIMETHYLAMINO)-2-HYDROXYBENZOYL]BENZOYL}AMINO)AZEPAN-3-YL]ISONICOTINAMIDE, cAMP-dependent protein kinase inhibitor, alpha form, ... Authors: Breitenlechner, C.B, Friebe, W.-G, Brunet, E, Werner, G, Graul, K, Thomas, U, Kuenkele, K.-P, Schaefer, W, Gassel, M, Bossemeyer, D, Huber, R, Engh, R.A, Masjost, B. Deposit date: 2004-09-17 Release date: 2005-09-17 Last modified: 2024-11-20 Method: X-RAY DIFFRACTION (2.45 Å) Cite: Design and crystal structures of protein kinase B-selective inhibitors in complex with protein kinase A and mutants J.Med.Chem., 48, 2005

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2004-09-17
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