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Thaixylomolins A–C: Limonoids Featuring Two New Motifs from the Thai Xylocarpus moluccensis

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Figshare2016-02-19 更新2026-04-29 收录
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https://figshare.com/articles/dataset/Thaixylomolins_A_C_Limonoids_Featuring_Two_New_Motifs_from_the_Thai_i_Xylocarpus_moluccensis_i_/2394940
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Three limonoids named thaixylomolins A–C (1–3), featuring two new motifs, were isolated from the seeds of a Thai mangrove, Xylocarpus moluccensis. The absolute configurations of these limonoids were determined by extensive NMR investigations, single-crystal X-ray diffraction analysis, and circular-dichroism spectroscopy in combination with quantum-chemical calculations. Thaixylomolin B exhibited inhibitory activity against nitric oxide production in lipopolysaccharide and IFN-γ-induced RAW264.7 murine macrophages with an IC50 value of 84.3 μM.
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2016-02-19
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