The centromere is a unique part of the chromosome combining a conserved function with an extreme variability in its DNA sequence. Most of our knowledge about the functional centromere organization is

NIAID Data Ecosystem80

Data_Sheet_2_Functional Allium fistulosum Centromeres Comprise Arrays of a Long Satellite Repeat, Insertions of Retrotransposons and Chloroplast DNA.docx

着丝粒功能基因组学

卫星重复序列分析

The centromere is a unique part of the chromosome combining a conserved function with an extreme variability in its DNA sequence. Most of our knowledge about the functional centromere organization is

NIAID Data Ecosystem70

Mutation and selection explain why eukaryotic centromeric DNA is often A+T rich

着丝粒功能基因组学

分子进化

The reasons why centromeric DNA is often A+T rich are not understood. We have used chromosome engineering to replace native centromeric DNA with different test sequences at native centromeres in two d

NIAID Data Ecosystem80

Human chromosome 8 neodicentric cell line (MS4221) sequencing

着丝粒功能基因组学

染色体结构变异

The human chromosome 8 neodicentric cell line MS4221, which harbors a functional neocentromere at 8q21.2, was sequenced via long-read sequencing to resolve the VNTR at 8q21.2 and map the location of t

NIAID Data Ecosystem70

CENP-B binding sites in the genus Equus

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