Morchella mycelial polysaccharides alleviate alcoholic liver injury by modulating NOD-like receptor signaling pathway

Alcoholic liver disease (ALD) is one of the leading causes of preventable liver-related morbidity and mortality globally. Bioactive polysaccharides exhibit substantial poten-tial as functional foods and therapeutic agents for the prevention and treatment of al-coholic liver injury (ALI). Morchella, an edible and medicinal fungus, contains poly-saccharides with diverse biological activities. This study aimed to evaluate the protec-tive effects of polysaccharides extracted from Morchella mycelium on alcohol-induced liver injury and elucidate the underlying mechanisms.