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5mC and 5hmC genes in the aetiology of dilated cardiomyopathy
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创建时间：
2019-02-10
相关数据集
Data_Sheet_1_Cardiomyocyte Proliferative Capacity Is Restricted in Mice With Lmna Mutation.pdf
LMNA is one of the leading causative genes of genetically inherited dilated cardiomyopathy (DCM). Unlike most DCM-causative genes, which encode sarcomeric or sarcomere-related proteins, LMNA encodes n
NIAID Data Ecosystem110
Associations between high blood pressure and DNA methylation
Background High blood pressure is a major risk factor for cardiovascular disease and is influenced by both environmental and genetic factors. Epigenetic processes including DNA methylation potentially
NIAID Data Ecosystem40
Deletion of the RS domain in RBM20 leads to dilated cardiomyopathy
Human patients carrying genetic mutations in RBM20 develop a clinically aggressive dilated cardiomyopathy (DCM) characterized by early onset heart failure, high mortality, and sudden death, which is r
NIAID Data Ecosystem30
Genome wide DNA methylation sequencing of ischemic skeletal muscle from normal, hyperlipidemic and type 2 diabetic mice. Mus musculus
Objective: To define the role of epigenetics, particularly DNA methylation in adaptive vascular growth in hyperlipidemic and type 2 diabetic mouse models of hind limb ischemia Methods: Unilateral hind
NIAID Data Ecosystem60
importance of MTFP1 partners for mitochondrial function in the heart
Mitochondria are paramount to the metabolism and survival of cardiomyocytes. Here we show that Mitochondrial Fission Process 1 (MTFP1) is essential for cardiac structure and function. Constitutive k
NIAID Data Ecosystem40
